 
                        
                     
                        
                     PanCancer IO 360™ Panel
 PanCancer IO 360™ Panel  Breast Cancer 360™ Panel
 Breast Cancer 360™ Panel  Tumor Signaling 360 Panel
 Tumor Signaling 360 Panel  CD3/CD4/CD8
 CD3/CD4/CD8  Naive & Memory Markers
 Naive & Memory Markers  NK Cell Markers
 NK Cell Markers  Measure shifts in TCR diversity in response to disease or therapeutic treatments, simultaneously measure TCR diversity and T cell phenotype with a streamlined workflow
 Measure shifts in TCR diversity in response to disease or therapeutic treatments, simultaneously measure TCR diversity and T cell phenotype with a streamlined workflow  Obtain a report with a TCR diversity score for each sample
 Obtain a report with a TCR diversity score for each sample  CD3/CD4/CD8
 CD3/CD4/CD8  Naive & Memory Markers
 Naive & Memory Markers  NK Cell Markers
 NK Cell Markers  Measure shifts in TCR diversity in response to disease or therapeutic treatments, simultaneously measure TCR diversity and T cell phenotype with a streamlined workflow
 Measure shifts in TCR diversity in response to disease or therapeutic treatments, simultaneously measure TCR diversity and T cell phenotype with a streamlined workflow  Obtain a report with a TCR diversity score for each sample
 Obtain a report with a TCR diversity score for each sample  CD3/CD4/CD8
 CD3/CD4/CD8  Naive & Memory Markers
 Naive & Memory Markers  NK Cell Markers
 NK Cell Markers  Measure shifts in TCR diversity in response to disease or therapeutic treatments, simultaneously measure TCR diversity and T cell phenotype with a streamlined workflow
 Measure shifts in TCR diversity in response to disease or therapeutic treatments, simultaneously measure TCR diversity and T cell phenotype with a streamlined workflow  Obtain a report with a TCR diversity score for each sample
 Obtain a report with a TCR diversity score for each sample  CD3/CD4/CD8
 CD3/CD4/CD8  Naive & Memory Markers
 Naive & Memory Markers  NK Cell Markers
 NK Cell Markers  Measure shifts in TCR diversity in response to disease or therapeutic treatments, simultaneously measure TCR diversity and T cell phenotype with a streamlined workflow
 Measure shifts in TCR diversity in response to disease or therapeutic treatments, simultaneously measure TCR diversity and T cell phenotype with a streamlined workflow  Obtain a report with a TCR diversity score for each sample
 Obtain a report with a TCR diversity score for each sample  Optimize CAR-T method development
 Optimize CAR-T method development  Create manufacturing acceptance criteria
 Create manufacturing acceptance criteria  Measure metabolic fitness and persistence
 Measure metabolic fitness and persistence  Monitor post-infusion exhaustion and toxicity
 Monitor post-infusion exhaustion and toxicity  Comprehensive gene expression analysis of cancer progression
 Comprehensive gene expression analysis of cancer progression  Quantify gene expression of metastatic growth and suppressor genes
 Quantify gene expression of metastatic growth and suppressor genes  Rapidly and easily screen samples for biomarker discovery or drug mechanism of action to support your research
 Rapidly and easily screen samples for biomarker discovery or drug mechanism of action to support your research  
                                             Profile 800 genes across 47 annotated pathways involved in canine immune response to IO treatments
 Profile 800 genes across 47 annotated pathways involved in canine immune response to IO treatments  Overlapping content with NanoString’s Human PanCancer IO 360 and PanCancer Immune Profiling Panels provides a suite of panels for comparative studies
 Overlapping content with NanoString’s Human PanCancer IO 360 and PanCancer Immune Profiling Panels provides a suite of panels for comparative studies  PanCancer coverage with tumor specific content for top canine cancers including Melanoma, Osteosarcoma, Lymphoma, Urothelial Carcinoma, and Glioblastoma.
 PanCancer coverage with tumor specific content for top canine cancers including Melanoma, Osteosarcoma, Lymphoma, Urothelial Carcinoma, and Glioblastoma.                                         
                    
                 Ideal for the study of allergy, autoimmune diseases, and the immune response to infectious disease
 Ideal for the study of allergy, autoimmune diseases, and the immune response to infectious disease  Unique mouse genes address known differences such as unique receptor ligands, Ig receptors and chemokines
 Unique mouse genes address known differences such as unique receptor ligands, Ig receptors and chemokines  Over 500 general immunology genes.
 Over 500 general immunology genes.  Therapeutic mechanism of action (MOA) studies
 Therapeutic mechanism of action (MOA) studies  Immunotherapy-induced adverse event investigations
 Immunotherapy-induced adverse event investigations  Discovery/validation of disease and therapeutic specific biomarkers
 Discovery/validation of disease and therapeutic specific biomarkers  Development of predictive signatures of drug response
 Development of predictive signatures of drug response  Compatible with challenging sample types such as PBMCs and FFPE
 Compatible with challenging sample types such as PBMCs and FFPE  Mechanisms of immune evasion
 Mechanisms of immune evasion  Damage response, wound healing & tissue repair
 Damage response, wound healing & tissue repair  Immune regulation
 Immune regulation  Disease pathogenesis
 Disease pathogenesis  Treatment response vs. non-response
 Treatment response vs. non-response  Study the immune response to transplanted tissue
 Study the immune response to transplanted tissue  Discover biomarkers for organ rejection and tissue damage for kidney, heart, liver, and lung
 Discover biomarkers for organ rejection and tissue damage for kidney, heart, liver, and lung  Evaluate immunosuppressive drug pathways
 Evaluate immunosuppressive drug pathways  Understand mechanisms behind drug-induced toxicity
 Understand mechanisms behind drug-induced toxicity  Identify BK Polyomavirus, Cytomegalovirus, and Epstein-Barr virus
 Identify BK Polyomavirus, Cytomegalovirus, and Epstein-Barr virus  Quantify the relative abundance of 14 different immune cells
 Quantify the relative abundance of 14 different immune cells  Content useful for the study of asthma, allergy, arthritis, and neurological-related inflammation
 Content useful for the study of asthma, allergy, arthritis, and neurological-related inflammation  Coverage of anti-inflammatory drugs that modulate the inflammatory response
 Coverage of anti-inflammatory drugs that modulate the inflammatory response  Overlapping coverage between Human and Mouse panels for direct species comparison
 Overlapping coverage between Human and Mouse panels for direct species comparison  Elucidate the mechanism of action behind the four stages of fibrosis: initiation, inflammation, proliferation, and modification
 Elucidate the mechanism of action behind the four stages of fibrosis: initiation, inflammation, proliferation, and modification  Understand the signaling cascade from cell stress to inflammation
 Understand the signaling cascade from cell stress to inflammation  Quantify the relative abundance of 14 different immune cell types
 Quantify the relative abundance of 14 different immune cell types 
 Host Susceptibility
 Host Susceptibility  Interferon Response
 Interferon Response  Innate Immune Cell Activation
 Innate Immune Cell Activation  Adaptive Immune Response
 Adaptive Immune Response  Homeostasis
 Homeostasis  Develop signatures of host response dynamics
 Develop signatures of host response dynamics  Immune Activation
 Immune Activation  Immune Suppression
 Immune Suppression  Immune Status
 Immune Status  Immune Checkpoints
 Immune Checkpoints  Epigenetics
 Epigenetics  Metabolism & Microenvironment
 Metabolism & Microenvironment  Mechanisms of immune evasion
 Mechanisms of immune evasion  Damage response, wound healing & tissue repair
 Damage response, wound healing & tissue repair  Immune regulation
 Immune regulation  Disease pathogenesis
 Disease pathogenesis  Treatment response vs. non-response
 Treatment response vs. non-response  
                                    
 Cell stress & Damage Response
 Cell stress & Damage Response  Pathways Regulating Glia
 Pathways Regulating Glia  Inflammation & Peripheral Immune Invasion
 Inflammation & Peripheral Immune Invasion  Glial Cell Homeostasis & Activation
 Glial Cell Homeostasis & Activation  Neurotransmission
 Neurotransmission  Quantify the relative abundance of 5 CNS cell types and 14 peripheral immune cells
 Quantify the relative abundance of 5 CNS cell types and 14 peripheral immune cells  Gene expression profiling of neuroimmune interactions
 Gene expression profiling of neuroimmune interactions  The study of drug treatment response and signature generation
 The study of drug treatment response and signature generation  Biomarker characterization
 Biomarker characterization  Research of neurodegenerative disease, traumatic brain injury, psychiatric disorders, neuropathic pain, CNS infection, and others
 Research of neurodegenerative disease, traumatic brain injury, psychiatric disorders, neuropathic pain, CNS infection, and others  Developed for research of Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis, Frontotemporal Dementia, Huntington's Disease, and other neurological disorders
 Developed for research of Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis, Frontotemporal Dementia, Huntington's Disease, and other neurological disorders  Includes unique cell typing feature for measuring the abundance of five important CNS cell types, including neurons, astrocytes, microglia, oligodendrocytes, and endothelial cells
 Includes unique cell typing feature for measuring the abundance of five important CNS cell types, including neurons, astrocytes, microglia, oligodendrocytes, and endothelial cells  770 gene made-to-order panel for human or mouse built as a Custom CodeSet
 770 gene made-to-order panel for human or mouse built as a Custom CodeSet  Comprehensive assessment of 30 AD-associated gene co-expression modules including 23 neurodegeneration pathways and processes
 Comprehensive assessment of 30 AD-associated gene co-expression modules including 23 neurodegeneration pathways and processes  Reproducible monitoring of AD progression with age
 Reproducible monitoring of AD progression with age  Functional screening of potential AD therapeutics
 Functional screening of potential AD therapeutics  AD characterization customizable with up to 55 additional user-defined genes with Panel Plus option
 AD characterization customizable with up to 55 additional user-defined genes with Panel Plus option 
 Study processes known to impact gene therapy development and manufacturing
 Study processes known to impact gene therapy development and manufacturing  Understand factors influencing optimal gene therapy development and manufacturing
 Understand factors influencing optimal gene therapy development and manufacturing  Monitor for toxicities
 Monitor for toxicities  Quantify the presence and relative abundance of different immune cell types present during therapy
 Quantify the presence and relative abundance of different immune cell types present during therapy  Customize to incorporate therapy specific biology, enabling parallel monitoring of therapy and host response biology
 Customize to incorporate therapy specific biology, enabling parallel monitoring of therapy and host response biology  Stemness
 Stemness  Pluripotency
 Pluripotency  Regulatory Signaling
 Regulatory Signaling  Epigenetics
 Epigenetics  Mechano-Signaling
 Mechano-Signaling  Metabolism
 Metabolism  Differentiation Signaling
 Differentiation Signaling  Lineage Specification
 Lineage Specification 
 Cardiovascular Pathology
 Cardiovascular Pathology  Cardiovascular Physiology
 Cardiovascular Physiology  Vascular Inflammation
 Vascular Inflammation  Cellular Aging & Renewal
 Cellular Aging & Renewal  Metabolism
 Metabolism  Mechano Signaling
 Mechano Signaling  Regulatory Signaling
 Regulatory Signaling  Epigenetic Remodeling
 Epigenetic Remodeling 
