At the leading-edge of genomic science, data analysis is getting complicated. Knowing what analysis to perform, how to wield the available analytical tools and how to visualize and interpret results are critical.
Majority of the Genomics work generates huge data with difficult to analyze and interpretation. Transform your research data into a captivating discovery story and narrate it with visually stunning plots and graphics! Our team provides diverse types of bioinformatics insights to support discovery and translational research. Talk to us, analyse your data and get greater biological insights.
When your assays are performed at theraCUES, raw and normalised data are always included and advanced analysis is performed on request.
If you cannot find the bioinformatics service you need, contact us to discuss your project!
Targeted Gene expression-Genes involved in core panel specific pathways along with optimized Housekeeping genes. Cell Type Profiling- Estimation of abundance of > 13 different Immune / Cancer-Immune cell types. Data Visualization- Visualize the gene expression results ranging from QC plots to pathway level regulation Gene Deregulation- Fold change in Up/ Downregulation of any gene against Control. Pathway Level Expression- Condense each sample's gene expression profile into a small set of pathway scores. Drug resistance specific gene identification using multiOMICS Drug mechanism of action via Gene expression analysis Pathways targeted by drugs and their expression regulation Identification of genes modulated by Dose and Time of drug treatment Signature gene identification based on multiple drug treatment 
Figure 1: Timepoint wise modulations for selected targets at selected dose
Figure 2: Dose wise modulations for selected targets at selected time-point
Sample clustering plots-
Differential expression analysis:
Pathway analysis:
Spatial Deconvolution:
High quality image of the ROI/AOI selected from tissue
Sample clustering Differential gene expression Functional enrichment reports (Gene ontology – Biological process, Cellular Component, Molecular Function & KEGG/REACTOME pathways) Supporting visualization at each step (PCA/UMAP/tSNE plots, Heatmaps, Volcano plots, Functional enrichment gradient plots, KEGG pathview maps and many more..!) Raw & QC Trimmed data (.fastq files) and QC reports per sample Mapped data (.BAM) files per sample and related QC reports Variant call results per sample and combined matrix – per sample VCF and merged VCF file. Annotated Variant call file (xlsx/ .csv format) - Functional as well as Pathogenic effect annotation included; per variant type (INDEL/SNP) OTU detection table and abundance profile for each samples Taxonomic assignment and abundance table Diversity analysis Gene expression matrix : Matrix, Barcodes and Feature files QC Reports per tissue/sample Cell clustering (UMAP/ tSNE) Report for Markers/ DEGs per cluster Cell type assignment report Single cell trajectory report Functional enrichment analysis report
